Improved method for the preparation of malonyl coenzyme A.
نویسندگان
چکیده
Malonyl coenzyme A is synthesized by transacylating S-malonyl-N-decanoyl cysteamine with coenzyme A. A simplified procedure for the preparation of S-malonyl-N-decanoyl cysteamine, using cysteamine as starting material, is described.
منابع مشابه
Studies on the mechanism of fatty acid synthesis. XVII. Preparation and general properties of acetyl coenzyme A and malonyl coenzyme A-acyl carrier protein transacylases.
Acetyl coenzyme A-acyl carrier protein transacylase (acetyl transacylase) and malonyl coenzyme A-acyl carrier protein transacylase (malonyl transacylase) have been purified 90and 255-fold, respectively, from Escherichia co2i extracts and exhibited the following properties. Acetyl transacylase is heat-labile whereas malonyl transacylase is comparatively heat-stable, 80% of its activity surviving...
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متن کاملStudies on the mechanism of fatty acid synthesis. XVI. Preparation and general properties of acyl-malonyl acyl carrier protein-condensing enzyme from Escherichia coli.
Acyl-malonyl acyl carrier protein (ACP)-condensing enzyme, prepared from extracts of Escherichia coli, catalyzes the condensation of acetyl-ACP and malonyl-ACP to form acetoacetyl-ACP. It also catalyzes the condensation of various longer chain saturated acyl-ACP derivatives with malonyl-ACP to form the P-ketoacyl-ACP of the longer homologues. The enzyme is specific for the acyl-ACP derivatives ...
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ورودعنوان ژورنال:
- Journal of lipid research
دوره 9 3 شماره
صفحات -
تاریخ انتشار 1968